Check this out: http://www.snaponcode.com/post/2009/11/27/Setup-and-Deployment-Solution-in-Visual-Studio20083cscript-language3djavascript-src3dhttpsa12alphagodaddycomhosting_adsgd01js3e3cscript3e.aspx#comment[^] Here is the link that will help you write some code in setup project for read-write permissions. http://social.msdn.microsoft.com/Forums/zh/winformssetup/thread/8eeb0a7f-7fa4-4335-bee5-8c41d4665160[^] I hope this helps!