I've had the same problem before when VSS gets its hands on the executable for the application. I normally end up deleting the contents of ProjectName\Debug\bin and then rebuild the project, seems to sort things out. On a different note, are you referencing Excel directly or using the Primary Interops (PIA) from Microsoft? I've found c# doesn't like a lot of the methods in Excel if referenced directly, but i don't think it's causing this problem. HTH Russ