The native pointer can point to any address. Please explain why you want to use native pointer to managed resource? It is very incorrect way. I think you should change your architecture instead of making such a thing. If you want to call managed code (method of managed object) from unmanaged context you should use callback. Handle can not point to native heap, but IntPtr can.

It is possible to recompile native code as managed code. You can build wrapper class to expose unmanaged C++ code in CLI. Then you can use managed infrastructure in your code. Check G. Hogenson "C++/CLI" book.