There is no "SendMouse" or "SendClick" so you have to use the Win32 API functions FindWindowEx to get the window that the image is in, get it's window handle, then use the API function SendMessage to send carefully crafted WM_LBUTTONDOWN and WM_LBUTTONUP messages to that window. Warning: This is NOT something for beginners!! You have to have specific knowledge of how Windows works and how your application works. If you don't have sufficient research skills, you'll find this a very frustrating experience.
A guide to posting questions on CodeProject[^]
Dave Kreskowiak Microsoft MVP Visual Developer - Visual Basic
2006, 2007