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  4. Evolution works in mysterious ways

Evolution works in mysterious ways

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  • L Lost User

    These are the ways a genome can change: Point mutation - change of one nucleotide to another - no information loss, can cause the acquisition of new features (e.g. antibiotic resistance) Insertion - insertion of 1+ nucleotides Deletion - removal of 1+ nucleotides Duplication - a gene can be duplicated Translocation - a gene can be placed under the control of another promoter Inversion - can have weird and interesting effects, but does appear to occur regularly Transformation/Conjugation - prokaryotes sharing genes or groups of genes Infection/Transduction - the integration of a viral genome - which can then be adapted to other purposes - see ERVs If I define 'information' as the number of functional genes in a species population's genome, then there are numerous ways that information increases. A gene is duplicated, mutates, is placed under the control of a different promoter so it is used for a different function. Very common if you believe the DNA evidence - but somehow I don't think you do. :laugh: Go BLAST it for yourself and see.

    - F

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    Matthew Faithfull
    wrote on last edited by
    #72

    Fisticuffs wrote:

    Point mutation - change of one nucleotide to another

    Can constitute information loss, has a high probability of disrupting any exisitng gene function.

    Fisticuffs wrote:

    Insertion - insertion of 1+ nucleotides

    Has a high probability of disrupting any exisiting gene function. This along with the above is the 'traditional' model of gene mutation driven evolution which has been shown to be inadequate to explain observation.

    Fisticuffs wrote:

    Deletion - removal of 1+ nucleotides

    Information loss, has a high probability of disrupting any exisitng gene function.

    Fisticuffs wrote:

    Translocation - a gene can be placed under the control of another promoter

    Information neutral. All necessary information gain must already have occured to form the potentially useful gene.

    Fisticuffs wrote:

    Inversion - can have weird and interesting effects, but does appear to occur regularly

    Information neutral over a population as nothing is added or removed, will be destructive or neutral in the majority of cases where a gene is functional.

    Fisticuffs wrote:

    Transformation/Conjugation

    Information neutral?

    Fisticuffs wrote:

    Infection/Transduction

    Do non destrcutive casses occur in nature? If so could they ever occur to any effect in a multi cellular organism. Not a lot of information increase there. Granted we probably have different concepts of information. None of the mechanisms you mention is capable of producing the observed species even given the unrealistic time frames usually quoted. You might also want to note that these are the ways we know of that a genome can change. Especially as you're going to need to find some new ones to hold on to your evolutionary delusion. :)

    "The secret of happiness is freedom, and the secret of freedom, courage." Thucydides (B.C. 460-400)

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    • 7 73Zeppelin

      For sure. It's the Great Deceit (TM)! Faithfull, lives in his own private fantasy world. He's delusional to some extent. You have to forgive him for his erroneous view of the world. It's his defense mechanism.

      M Offline
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      Matthew Faithfull
      wrote on last edited by
      #73

      I feel much the same about you.

      "The secret of happiness is freedom, and the secret of freedom, courage." Thucydides (B.C. 460-400)

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      • O Oakman

        73Zeppelin wrote:

        Faithfull, lives in his own private fantasy world

        While it's hard to understand exactly what he's babbling about, I think he's claiming that the neaderthals were a higher life form and we have devolved from them. Hard to think of Adam and Eve with single eyebrows, unbridged noses, and weak chins.

        Jon Smith & Wesson: The original point and click interface

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        Matthew Faithfull
        wrote on last edited by
        #74

        Oakman wrote:

        Hard to think of Adam and Eve with single eyebrows, unbridged noses, and weak chins.

        You've been talking to the wrong neanderthals my friend. I guess even you'd swap a bridged nose for a larger brain and a 1000 year life span. :laugh:

        "The secret of happiness is freedom, and the secret of freedom, courage." Thucydides (B.C. 460-400)

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        • M Matthew Faithfull

          Ravel H. Joyce wrote:

          Pathogens evolve a resistance to antibiotics.

          No, even evolutionists don't claim that. The pathogens already have within their populations a proportion that are immune due to genetic variations. When you look into how these immunities actually work you find they usually fall into the catagery of de-evolutionary specialisations, for example having damaged protiens causing slower metabolism making them more tolerant of toxins. On the scale of microbes the functioanlities are simple enough and the information density of the genomes low enough that an occassional functional novelty can appear, some of these have been documented. This however doesn't change the fact that a bacteria remains a bacteria and can't ever become anything else. It can't grow legs because the set of information required for legs is too large complex and interrelated to come about through truly random changes. Survival of the fitest doesn't help because having half the genes for a leg doesn't make you any fitter than having none of them and in a small genome has a very high probability of meaning something else gets damaged or lost that you do need to survive. As I've said many times, in practice, the mechanisms proposed by biologists to cause evolution, don't. They cause de-evolution.

          Ravel H. Joyce wrote:

          Evolution is very scientific. How isn't it?

          It does not follow the scientific method of proposing an idea, attempting to falsify it and on succeeding replacing it with a better idea. It rather follows the path of false religions everywhere, propose an idea, reinterpret everything in relation to that idea ( hence evolutionary biology ), especially any contrary evidence and when the idea is still clearly nonsense replace it on the quiet with another while denying having done so, hence Stan's pathetic attempt to define evolution as anything that happens to genes. :doh:

          "The secret of happiness is freedom, and the secret of freedom, courage." Thucydides (B.C. 460-400)

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          Lost User
          wrote on last edited by
          #75

          Matthew Faithfull wrote:

          he pathogens already have within their populations a proportion that are immune due to genetic variations.

          Wrong. De novo mutations conferring resistance over time and appropriate exposure has been demonstrated in the lab.

          Matthew Faithfull wrote:

          When you look into how these immunities actually work you find they usually fall into the catagery of de-evolutionary specialisations, for example having damaged protiens causing slower metabolism making them more tolerant of toxins.

          Wrong. In certain cases, the mutations confer a higher growth rate and stability to the organism. This would also be true by definition - mutations that enable an organism to survive in a stressor (artificial or not) still means they survive, even if there is a cost.

          Matthew Faithfull wrote:

          This however doesn't change the fact that a bacteria remains a bacteria and can't ever become anything else. It can't grow legs because the set of information required for legs is too large complex and interrelated to come about through truly random changes.

          Misrepresentation of evolutionary theory. Bacteria do not become horses, bacteria and horses share a common ancestor. The distinction is critical.

          Matthew Faithfull wrote:

          s I've said many times, in practice, the mechanisms proposed by biologists to cause evolution, don't. They cause de-evolution.

          As Ravel has pointed out, your semantic distinction between evolution and "deevolution" is nothing but rhetoric, devoid of meaning.

          Matthew Faithfull wrote:

          It does not follow the scientific method of proposing an idea, attempting to falsify it and on succeeding replacing it with a better idea.

          Untrue. Evolution could be falsified easily by never finding any fossil variation, never seeing any extinct species, finding an ancestral species and a modern species in the same dated strata, not seeing any variation in population genomes that are differentially selected on, not being able to demonstrate the development of new features under selective pressures in a lab in the expected timeframe, etc etc etc. So far, evolution has not been falsified, despite best efforts.

          - F

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          • L leckey 0

            Can you really believe in an idea that resulted in a band calling themselves Devo? (You're young so I don't know if you have heard them.)

            CP Offenders: Over 50 offenders and growing! Current rant: "Me thinks CP needs an application process!" http://craptasticnation.blogspot.com/[^]

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            Matthew Faithfull
            wrote on last edited by
            #76

            I can believe in what the evidence shows, is consistent with the rest of science and makes logical sense. If some 70's band members can do the same then good for them. :cool:

            "The secret of happiness is freedom, and the secret of freedom, courage." Thucydides (B.C. 460-400)

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            • 7 73Zeppelin

              I knew you wouldn't couldn't answer my questions. The reason? Because your remarks are meaningless and made up on the spot.

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              Matthew Faithfull
              wrote on last edited by
              #77

              If you really want to understand information theory I suggest you look at this guys[^] books. You will definitely learn something, probably more than me with your mathematical bent.

              "The secret of happiness is freedom, and the secret of freedom, courage." Thucydides (B.C. 460-400)

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              • M Matthew Faithfull

                Fisticuffs wrote:

                Point mutation - change of one nucleotide to another

                Can constitute information loss, has a high probability of disrupting any exisitng gene function.

                Fisticuffs wrote:

                Insertion - insertion of 1+ nucleotides

                Has a high probability of disrupting any exisiting gene function. This along with the above is the 'traditional' model of gene mutation driven evolution which has been shown to be inadequate to explain observation.

                Fisticuffs wrote:

                Deletion - removal of 1+ nucleotides

                Information loss, has a high probability of disrupting any exisitng gene function.

                Fisticuffs wrote:

                Translocation - a gene can be placed under the control of another promoter

                Information neutral. All necessary information gain must already have occured to form the potentially useful gene.

                Fisticuffs wrote:

                Inversion - can have weird and interesting effects, but does appear to occur regularly

                Information neutral over a population as nothing is added or removed, will be destructive or neutral in the majority of cases where a gene is functional.

                Fisticuffs wrote:

                Transformation/Conjugation

                Information neutral?

                Fisticuffs wrote:

                Infection/Transduction

                Do non destrcutive casses occur in nature? If so could they ever occur to any effect in a multi cellular organism. Not a lot of information increase there. Granted we probably have different concepts of information. None of the mechanisms you mention is capable of producing the observed species even given the unrealistic time frames usually quoted. You might also want to note that these are the ways we know of that a genome can change. Especially as you're going to need to find some new ones to hold on to your evolutionary delusion. :)

                "The secret of happiness is freedom, and the secret of freedom, courage." Thucydides (B.C. 460-400)

                L Offline
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                Lost User
                wrote on last edited by
                #78

                That's kind of disingenuous, don't you think? Ignore the one absolutely clear event that causes information gain? The one that happens all the time, as I said? Which you ignored?

                Matthew Faithfull wrote:

                Do non destrcutive casses occur in nature? If so could they ever occur to any effect in a multi cellular organism.

                Yes. As I said, look how ERVs have been adapted to new functions in the human genome. Look it up.

                Matthew Faithfull wrote:

                Fisticuffs wrote: Transformation/Conjugation Information neutral?

                No. Bacteria A shares features with bacteria B. Bacteria B now has both A and B's gene. Those genes are then adapted to new function. Information gain. Also, while most mutations may be deleterious over enough time (as has been demonstrated) beneficial mutations can occur and accumulate after selection. So basically, you ignored most of what I said. Well, this has been productive. :rolleyes:

                - F

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                • M Matthew Faithfull

                  If you really want to understand information theory I suggest you look at this guys[^] books. You will definitely learn something, probably more than me with your mathematical bent.

                  "The secret of happiness is freedom, and the secret of freedom, courage." Thucydides (B.C. 460-400)

                  L Offline
                  L Offline
                  Lost User
                  wrote on last edited by
                  #79

                  That makes sense. :rolleyes:

                  - F

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                  • H Haydn Chapman

                    Matthew Faithfull wrote:

                    As I've said many times, in practice, the mechanisms proposed by biologists to cause evolution, don't. They cause de-evolution.

                    So are you saying that everything started of as being Perfect? Every organism at the beginning of time (whenever that is supposed to be), was as good as it could possibly be? Other that God putting them there, how did they all start off? And does that mean we are getting more and more sickly, unhealthy, weaker etc.... as the years go on because we lose certain parts of our dna making us less human so to speak? I just want to know what the theory of de-evolution actually is, because I'm not too familiar with it and it doesn't seem to be as intuitive to understand as evolution.

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                    Matthew Faithfull
                    wrote on last edited by
                    #80

                    John Davids wrote:

                    So are you saying that everything started of as being Perfect?

                    Yes.

                    John Davids wrote:

                    Every organism at the beginning of time (whenever that is supposed to be), was as good as it could possibly be?

                    Yes, God, who's standard is perfection, examined what he had made and declared that it was good.

                    John Davids wrote:

                    Other that God putting them there,

                    There is no other.

                    John Davids wrote:

                    And does that mean we are getting more and more sickly, unhealthy, weaker etc.... as the years go on because we lose certain parts of our dna making us less human so to speak?

                    Yes. We are less than our ancestors and if we were to continue as a species for a very long time we would be much less. The diminishing is mitigated to an extent by massive population growth preserving genetic information by duplication but in the end entropy will have its way.

                    "The secret of happiness is freedom, and the secret of freedom, courage." Thucydides (B.C. 460-400)

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                    • L Lost User

                      Matthew Faithfull wrote:

                      he pathogens already have within their populations a proportion that are immune due to genetic variations.

                      Wrong. De novo mutations conferring resistance over time and appropriate exposure has been demonstrated in the lab.

                      Matthew Faithfull wrote:

                      When you look into how these immunities actually work you find they usually fall into the catagery of de-evolutionary specialisations, for example having damaged protiens causing slower metabolism making them more tolerant of toxins.

                      Wrong. In certain cases, the mutations confer a higher growth rate and stability to the organism. This would also be true by definition - mutations that enable an organism to survive in a stressor (artificial or not) still means they survive, even if there is a cost.

                      Matthew Faithfull wrote:

                      This however doesn't change the fact that a bacteria remains a bacteria and can't ever become anything else. It can't grow legs because the set of information required for legs is too large complex and interrelated to come about through truly random changes.

                      Misrepresentation of evolutionary theory. Bacteria do not become horses, bacteria and horses share a common ancestor. The distinction is critical.

                      Matthew Faithfull wrote:

                      s I've said many times, in practice, the mechanisms proposed by biologists to cause evolution, don't. They cause de-evolution.

                      As Ravel has pointed out, your semantic distinction between evolution and "deevolution" is nothing but rhetoric, devoid of meaning.

                      Matthew Faithfull wrote:

                      It does not follow the scientific method of proposing an idea, attempting to falsify it and on succeeding replacing it with a better idea.

                      Untrue. Evolution could be falsified easily by never finding any fossil variation, never seeing any extinct species, finding an ancestral species and a modern species in the same dated strata, not seeing any variation in population genomes that are differentially selected on, not being able to demonstrate the development of new features under selective pressures in a lab in the expected timeframe, etc etc etc. So far, evolution has not been falsified, despite best efforts.

                      - F

                      M Offline
                      M Offline
                      Matthew Faithfull
                      wrote on last edited by
                      #81

                      Fisticuffs wrote:

                      Wrong. De novo mutations conferring resistance over time and appropriate exposure has been demonstrated in the lab.

                      In bacteria as I freely conceeded.

                      Fisticuffs wrote:

                      Wrong. In certain cases, the mutations confer a higher growth rate and stability to the organism. This would also be true by definition - mutations that enable an organism to survive in a stressor (artificial or not) still means they survive, even if there is a cost.

                      If the cost makes the species more prone to extinction then there is no species evolution only specialisation towards a dead end.

                      Fisticuffs wrote:

                      Bacteria do not become horses, bacteria and horses share a common ancestor. The distinction is critical.

                      Drivel, the distinction is an irrelevance unless the ancestors of the bacteria contained the information necessary to grow a horse, i.e. an extreme de-evolutionary scenario.

                      Fisticuffs wrote:

                      As Ravel has pointed out, your semantic distinction between evolution and "deevolution" is nothing but rhetoric, devoid of meaning.

                      And he was wrong just as you are, de-evolution is unidirectional, to derive a mouse it requires a better mouse, evolution cannot create the better mouse or the mouse without having a mouse, it is nodirectional. :)

                      Fisticuffs wrote:

                      Evolution could be falsified easily by never finding any fossil variation

                      Double negative, is gravity falsifiable by never finding anything falling, no.

                      Fisticuffs wrote:

                      never seeing any extinct species

                      Extinct species are evidence of de-evolution.

                      Fisticuffs wrote:

                      finding an ancestral species and a modern species in the same dated strata

                      Happens frequently usually followed by a redating of the strata, ancestoral speicies is of course a derivative concept and cannot be used as evidence for evolution, that would be a circular argument. :laugh:

                      Fisticuffs wrote:

                      not seeing any variation in population genomes that are differentially selected on

                      Another, proof by blindness, double negative.

                      Fisticuffs wrote:

                      not being able to

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                      • S Stan Shannon

                        You're absolutely correct. However, just because evolution provides a better explanation of certain observable phenomenon, doesn't actually make it correct. It just makes it a better explanation. And it certainly does not imbue science with a more reasonable means for social order.

                        Please excuse my refusal to participate in the suicide of western civilization

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                        Oakman
                        wrote on last edited by
                        #82

                        Stan Shannon wrote:

                        You're absolutely correct.

                        :omg: :wtf: :wtf: :omg: :laugh:

                        Jon Smith & Wesson: The original point and click interface

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                        • M Matthew Faithfull

                          Oakman wrote:

                          Hard to think of Adam and Eve with single eyebrows, unbridged noses, and weak chins.

                          You've been talking to the wrong neanderthals my friend. I guess even you'd swap a bridged nose for a larger brain and a 1000 year life span. :laugh:

                          "The secret of happiness is freedom, and the secret of freedom, courage." Thucydides (B.C. 460-400)

                          O Offline
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                          Oakman
                          wrote on last edited by
                          #83

                          Matthew Faithfull wrote:

                          a larger brain and a 1000 year life span

                          And where did you learn about these creatures?

                          Jon Smith & Wesson: The original point and click interface

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                          • O Oakman

                            Stan Shannon wrote:

                            Did I include it?

                            Just checking. Remember, when you eat crackers in bed, you wake up with crumbs

                            Jon Smith & Wesson: The original point and click interface

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                            Ilion
                            wrote on last edited by
                            #84

                            Oakman wrote:

                            Remember, when you eat crackers in bed, you wake up with crumbs

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                            • M Matthew Faithfull

                              Ravel H. Joyce wrote:

                              how would that agree with the Bible?

                              In a word, completely. Of course you'd have to read quite a bit of the Bible to see that. For example the biblical perspective is that nature itself, i.e. physics, biology the whole works, was corrupted from its previous perfection at the fall, tainted with sin. The wages of sin, i.e. its long term outcome, is death. The working out of this principle can be seen in the laws of thermodynamics. The universe itself is running down to an end point already determined, the appointed day or 'the great and terrible day of the Lord' as it is described. The Bible is not a science text book but there is nothing false in it as there is nothing false in its author and therefore no disagreement with reality or with any honest scientific observation. To me de-evolution seems to fit entirely with what it says but if it turns out not be so then my de-evolutionary theory is flawed not Bible. The author of the universe knows best how it works and how to live in it.

                              "The secret of happiness is freedom, and the secret of freedom, courage." Thucydides (B.C. 460-400)

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                              Oakman
                              wrote on last edited by
                              #85

                              Matthew Faithfull wrote:

                              but there is nothing false in it as there is nothing false in its author

                              You have, of course, read it in the original Aramaic?

                              Jon Smith & Wesson: The original point and click interface

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                              • I Ilion

                                Oakman wrote:

                                Remember, when you eat crackers in bed, you wake up with crumbs

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                                Oakman
                                wrote on last edited by
                                #86

                                Gee now that you have shown up, someone is running around voting me all ones - Does it help you feel like you're a real man? Those exhibiting a superiority complex commonly project their feelings of inferiority onto others they perceive as beneath them, possibly for the same reasons they themselves may have been ostracized, i.e. viewing most, possibly all others as "ugly" or "stupid", and beneath oneself. Behaviors related to this mechanism may include an exaggeratedly positive opinion of one’s worth and abilities, unrealistically high expectations in goals and achievements for oneself and others, the persistent attempt to correct others regardless of whether they are factually correct or not, vanity, extravagant style in dressing (with intent of drawing attention), excessive need for competition, pride, sentimentalism and affected exaltation, snobbishness, and a tendency to try to discredit others' opinions, as well as forcefulness and hostility aimed at dominating those he has convinced himself are weaker or less important.

                                Jon Smith & Wesson: The original point and click interface

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                                • M Matthew Faithfull

                                  Oakman wrote:

                                  Hard to think of Adam and Eve with single eyebrows, unbridged noses, and weak chins.

                                  You've been talking to the wrong neanderthals my friend. I guess even you'd swap a bridged nose for a larger brain and a 1000 year life span. :laugh:

                                  "The secret of happiness is freedom, and the secret of freedom, courage." Thucydides (B.C. 460-400)

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                                  Lost User
                                  wrote on last edited by
                                  #87

                                  Matthew Faithfull wrote:

                                  and a 1000 year life span.

                                  Stop... you're killing me. :laugh: :laugh: :laugh: :laugh:

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                                  • L Lost User

                                    That's kind of disingenuous, don't you think? Ignore the one absolutely clear event that causes information gain? The one that happens all the time, as I said? Which you ignored?

                                    Matthew Faithfull wrote:

                                    Do non destrcutive casses occur in nature? If so could they ever occur to any effect in a multi cellular organism.

                                    Yes. As I said, look how ERVs have been adapted to new functions in the human genome. Look it up.

                                    Matthew Faithfull wrote:

                                    Fisticuffs wrote: Transformation/Conjugation Information neutral?

                                    No. Bacteria A shares features with bacteria B. Bacteria B now has both A and B's gene. Those genes are then adapted to new function. Information gain. Also, while most mutations may be deleterious over enough time (as has been demonstrated) beneficial mutations can occur and accumulate after selection. So basically, you ignored most of what I said. Well, this has been productive. :rolleyes:

                                    - F

                                    M Offline
                                    M Offline
                                    Matthew Faithfull
                                    wrote on last edited by
                                    #88

                                    Fisticuffs wrote:

                                    Also, while most mutations may be deleterious over enough time (as has been demonstrated) beneficial mutations can occur and accumulate after selection.

                                    This is the key point and why you need to understand some mathematics. Lets break it down. "most mutations may be deleterious" These will accumulate until they become fatal, i.e. 100% negative for passing on of genes. "Beneficial mutations can occur and accumulate after selection" These will accumulate faster until they take over the population but only if they actually confer selective advantage. If the probability of the mutation being deleterious is too high deleterious mutations will always swamp beneficial ones regardless of selective advantage especially as they will accumulate in those survivors which have the selective advantage until they cause equal selective disadvantage. I hope you can see the problem. Only mutations which confer immediate benefit actaully confer any selective advantage and that is only probabalistic. These cannot survive long enough to build into complex features because they are swamped by the higher probability deleterious mutations that cannot be avoided in each generation. The only way to get a complex feature is for it to slip through by chance. When you work out the probability of this actually occuring it is less than that of spontaneous generation. :laugh: More time does not help you, only more mutations per generation could do that, it just makes things worse. Mathematics has a thing called proof by induction which can be used to show that if your species doesn't evolve over n generations then it doesn't evolve over 2n either. If it de-evolves over n generations then it's going to be extinct in some multiple of n. Interestingly the 'more mutations per generation' model has been tried and found to be even worse, ie, more destructive. Again simple math tells you if more at once is bad then more generations of a little is also bad. It's the 'if you're in a hole stop digging' principle. I only wish evolutionists would get it and stop wasting their time.

                                    "The secret of happiness is freedom, and the secret of freedom, courage." Thucydides (B.C. 460-400)

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                                    • O Oakman

                                      Matthew Faithfull wrote:

                                      a larger brain and a 1000 year life span

                                      And where did you learn about these creatures?

                                      Jon Smith & Wesson: The original point and click interface

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                                      Matthew Faithfull
                                      wrote on last edited by
                                      #89

                                      Same places you learned about Adam and Eve and about neanderthals ( which probably never existed as anything other than a tribal variation of humans ). Appears we understood what we were hearing to a differing degree. :)

                                      "The secret of happiness is freedom, and the secret of freedom, courage." Thucydides (B.C. 460-400)

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                                      • L leckey 0

                                        I would maybe listen to someone who claims evolution never happened if they were atheist.

                                        CP Offenders: Over 50 offenders and growing! Current rant: "Me thinks CP needs an application process!" http://craptasticnation.blogspot.com/[^]

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                                        Matthew Faithfull
                                        wrote on last edited by
                                        #90

                                        So you'd prefer to listen to someone who doesn't actually believe anything and has no moral restraint against telling you a pack of lies than to someone who holds a consistent set of beliefs including a moral imperative to tell you the truth, interesting. Your choice of course.

                                        "The secret of happiness is freedom, and the secret of freedom, courage." Thucydides (B.C. 460-400)

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                                        • R R Giskard Reventlov

                                          You believe in a god, do you not? Doesn't get any more fantasy based than that.

                                          me, me, me

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                                          Matthew Faithfull
                                          wrote on last edited by
                                          #91

                                          No, not a god but the one and only true and living God who is no fantasy. Isn't it fortunate for you that despite your unbelief he believes in you. After all you might have a problem with your continued existence otherwise :laugh:

                                          "The secret of happiness is freedom, and the secret of freedom, courage." Thucydides (B.C. 460-400)

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