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Old Age Sucks

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  • A Alan Balkany

    Google centrophenoxine. It's been shown repeatedly over several decades to improve memory in old organisms, but not young organisms. As cells age, they accumulate a waste product called lipofuscin faster than they can get rid of it. Centrophenoxine is the only drug known that causes cells to excrete lipofuscin. It's safe even in extremely large doses, and has also been shown to increase lifespan about 30%. It's unavailable in the US because the patent expired a long time ago, so no US drug company can make a profit on it, but it can be ordered from European companies. The recommended dose for short-term use is 1000 mg daily, but I think a smaller dose (250 mg three times a week) indefinitely is more effective. Another drug that slows brain aging is deprenyl. There's evidence it also may increase lifespan. It's used in doses of 5-10 mg and higher to treat seizures, but in much lower doses to slow brain aging. It requires a prescription. There's information about deprenyl at lef.org.

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    Simon P Stevens
    wrote on last edited by
    #23

    Alan Balkany wrote:

    has also been shown to increase lifespan about 30%.

    If it's that good why aren't we all taking it?

    Simon

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    • S Simon P Stevens

      Alan Balkany wrote:

      has also been shown to increase lifespan about 30%.

      If it's that good why aren't we all taking it?

      Simon

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      Alan Balkany
      wrote on last edited by
      #24

      The drug ads you seen on TV cost millions of dollars. It would also cost literally millions of dollars to get it approved in the US. Centrophenoxine is so cheap you can get a several-month supply of it for around $25. The economics don't provide for-profit organizations with the incentive to promote it.

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      • A Alan Balkany

        The drug ads you seen on TV cost millions of dollars. It would also cost literally millions of dollars to get it approved in the US. Centrophenoxine is so cheap you can get a several-month supply of it for around $25. The economics don't provide for-profit organizations with the incentive to promote it.

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        Simon P Stevens
        wrote on last edited by
        #25

        I live in the UK and I've never heard of it. Ok, I can see why it's not advertised over in the US, but surely here, if it's available and really does increase life expectancy by 30% doctors would just tell people about it. I'm just quite skeptical of 'miracle cures'.

        Simon

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        • S Simon P Stevens

          I live in the UK and I've never heard of it. Ok, I can see why it's not advertised over in the US, but surely here, if it's available and really does increase life expectancy by 30% doctors would just tell people about it. I'm just quite skeptical of 'miracle cures'.

          Simon

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          Alan Balkany
          wrote on last edited by
          #26

          Do a Google search for "free medline". Then do a Medline search for centrophenoxine (or related topics such as lipofuscin). This will give you the actual peer-reviewed journal medical articles published on centrophenoxine. Most of them have an abstract that summarizes the article's results. After some research you will find: 1. Lipofuscin accumulates with age, and causes damage in a variety of ways. 2. Centrophenoxine eliminates lipofuscin from cells. 3. Centrophenoxine improves memory in aged individuals. 4. Centrophenoxine increases lifespan. These are medical facts. The published results are from many different researchers in many different countries over many decades, and they report consistent results.

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          • A Alan Balkany

            The drug ads you seen on TV cost millions of dollars. It would also cost literally millions of dollars to get it approved in the US. Centrophenoxine is so cheap you can get a several-month supply of it for around $25. The economics don't provide for-profit organizations with the incentive to promote it.

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            Lost User
            wrote on last edited by
            #27

            Like hydrazine sulphate as a supportive treatment in cancer. It limits glucose output which limits tumour growth.

            Visit http://www.notreadytogiveup.com/[^] and do something special today.

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            • A Alan Balkany

              Do a Google search for "free medline". Then do a Medline search for centrophenoxine (or related topics such as lipofuscin). This will give you the actual peer-reviewed journal medical articles published on centrophenoxine. Most of them have an abstract that summarizes the article's results. After some research you will find: 1. Lipofuscin accumulates with age, and causes damage in a variety of ways. 2. Centrophenoxine eliminates lipofuscin from cells. 3. Centrophenoxine improves memory in aged individuals. 4. Centrophenoxine increases lifespan. These are medical facts. The published results are from many different researchers in many different countries over many decades, and they report consistent results.

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              Simon P Stevens
              wrote on last edited by
              #28

              I have googled a bit, and yes I have found sources that verify what you say, but I can't help but think that something is not being said. I'm not a drug expert, but surely if it was that good, people would be raving about it. There's other ways other than advertising that can spread a message. Surely something this effective would spread through word of mouth. Do you take it daily?

              Simon

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              • realJSOPR realJSOP

                My memory is failing. I copied some code to a thumb drive this morning intended to bring it to work, and left the damn thing at home. I do this a lot lately. A lot of times, I can't write code, leave it for more than a week, and be able to Pick up where I left off. I also find that I'm adding more comments to my code to help me remember what i was doing when I wrote it. I've also started commenting the hell outa my app.config files for the same reason (they often have more comments than settings). It sucks getting old...

                "Why don't you tie a kerosene-soaked rag around your ankles so the ants won't climb up and eat your candy ass..." - Dale Earnhardt, 1997
                -----
                "...the staggering layers of obscenity in your statement make it a work of art on so many levels." - Jason Jystad, 10/26/2001

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                Ennis Ray Lynch Jr
                wrote on last edited by
                #29

                I stood in an elevator once for thirty minutes at a not so busy office because I forgot to press the button.

                Need a C# Consultant? I'm available.
                Happiness in intelligent people is the rarest thing I know. -- Ernest Hemingway

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                • S Simon P Stevens

                  I have googled a bit, and yes I have found sources that verify what you say, but I can't help but think that something is not being said. I'm not a drug expert, but surely if it was that good, people would be raving about it. There's other ways other than advertising that can spread a message. Surely something this effective would spread through word of mouth. Do you take it daily?

                  Simon

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                  Alan Balkany
                  wrote on last edited by
                  #30

                  I take 250 mg three times a week. In the US, the medical industry is focused primarily on corporate profits. Things that don't contribute toward this goal are unimportant, and aren't advertised or communicated to doctors. This situation has caused people to call for taking the profit out of medicine by supporting a single-payer health care system. Unfortunately, the major political parties in the US receive most of their funding from corporations, so all discussion of such a system is silenced. And yet people continue to vote for these corrupt parties. The lack of publicity on centrophenoxine is a symptom of a much larger problem.

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                  • R R Giskard Reventlov

                    I gave you a 5 to balance the 1 cos I feel sorry for you being so old and decrepit. The I remembered who you are... :-) Oh, and the reason getting old sucks is cos you lose your teeth and that's the only way you can eat anything.

                    me, me, me

                    realJSOPR Offline
                    realJSOPR Offline
                    realJSOP
                    wrote on last edited by
                    #31

                    I hadn't even noticed the voting on it. Your sniffer goes out too. Coffee (and a lot of other things) doesn't smell right anymore. On the upside, you can't smell farts either...

                    "Why don't you tie a kerosene-soaked rag around your ankles so the ants won't climb up and eat your candy ass..." - Dale Earnhardt, 1997
                    -----
                    "...the staggering layers of obscenity in your statement make it a work of art on so many levels." - Jason Jystad, 10/26/2001

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                    • realJSOPR realJSOP

                      My memory is failing. I copied some code to a thumb drive this morning intended to bring it to work, and left the damn thing at home. I do this a lot lately. A lot of times, I can't write code, leave it for more than a week, and be able to Pick up where I left off. I also find that I'm adding more comments to my code to help me remember what i was doing when I wrote it. I've also started commenting the hell outa my app.config files for the same reason (they often have more comments than settings). It sucks getting old...

                      "Why don't you tie a kerosene-soaked rag around your ankles so the ants won't climb up and eat your candy ass..." - Dale Earnhardt, 1997
                      -----
                      "...the staggering layers of obscenity in your statement make it a work of art on so many levels." - Jason Jystad, 10/26/2001

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                      Mike HankeyM Offline
                      Mike Hankey
                      wrote on last edited by
                      #32

                      A friend of mine told me "getting old ain't for sissies" How true it is! Mike

                      You only need two tools in life - WD-40 and Duct Tape. If it doesn't move and should, use the WD-40. If it should't move and does, use the Duct Tape.
                      Semper Fi http://www.hq4thmarinescomm.com[^] My Site

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                      • realJSOPR realJSOP

                        My memory is failing. I copied some code to a thumb drive this morning intended to bring it to work, and left the damn thing at home. I do this a lot lately. A lot of times, I can't write code, leave it for more than a week, and be able to Pick up where I left off. I also find that I'm adding more comments to my code to help me remember what i was doing when I wrote it. I've also started commenting the hell outa my app.config files for the same reason (they often have more comments than settings). It sucks getting old...

                        "Why don't you tie a kerosene-soaked rag around your ankles so the ants won't climb up and eat your candy ass..." - Dale Earnhardt, 1997
                        -----
                        "...the staggering layers of obscenity in your statement make it a work of art on so many levels." - Jason Jystad, 10/26/2001

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                        Zdenek Navratil
                        wrote on last edited by
                        #33

                        There are 4 stages of getting old: 1. forget names 2. forget faces 3. forget to zip trousers 4. forget to unzip trousers Oh, s**t, I forget... My only excuse is I'm getting 61 next month :)

                        Regards,  Zdenek


                        Nothing is as persistent as a temporary solution (a lesson learned by experience)

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                        • D Dalek Dave

                          How many times do you walk into a room, stop dead and think "What did I come in here for?" I too am getting these 'Senior Moments' :confused:

                          ------------------------------------ "I want you to imagine I have a blaster in my hand" - Zaphod Beeblebrox. "You DO have a blaster in your hand" - Freighter Pilot "Yeah, so you don't have to tax your imagination too hard" - Zaphod Beeblebrox

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                          Xiangyang Liu
                          wrote on last edited by
                          #34

                          Dalek Dave wrote:

                          How many times do you walk into a room, stop dead and think "What did I come in here for?"

                          Not the ladies room, I hope. :-D

                          My .NET Business Application Framework My Home Page My Younger Son & His "PET"

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                          • Z Zdenek Navratil

                            There are 4 stages of getting old: 1. forget names 2. forget faces 3. forget to zip trousers 4. forget to unzip trousers Oh, s**t, I forget... My only excuse is I'm getting 61 next month :)

                            Regards,  Zdenek


                            Nothing is as persistent as a temporary solution (a lesson learned by experience)

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                            Oakman
                            wrote on last edited by
                            #35

                            Zdenek Navratil wrote:

                            My only excuse is I'm getting 61 next month

                            I remember 61. :zzz:

                            Jon Smith & Wesson: The original point and click interface

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                            • O Oakman

                              John Simmons / outlaw programmer wrote:

                              My memory is failing

                              They say memory is the second thing to go. I can't remember what the first is. . . :sigh:

                              Jon Smith & Wesson: The original point and click interface

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                              Xiangyang Liu
                              wrote on last edited by
                              #36

                              Oakman wrote:

                              They say memory is the second thing to go. I can't remember what the first is. . .

                              For me, it is eye sight. But now that my memory is gone, what the good of eye glasses if I keep forgetting where I put them? :-D

                              My .NET Business Application Framework My Home Page My Younger Son & His "PET"

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                              • D Dalek Dave

                                How many times do you walk into a room, stop dead and think "What did I come in here for?" I too am getting these 'Senior Moments' :confused:

                                ------------------------------------ "I want you to imagine I have a blaster in my hand" - Zaphod Beeblebrox. "You DO have a blaster in your hand" - Freighter Pilot "Yeah, so you don't have to tax your imagination too hard" - Zaphod Beeblebrox

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                                Gary Wheeler
                                wrote on last edited by
                                #37

                                I saw a woman in the store last weekend with a T-shirt that read:

                                I know I came into this room for a reason...

                                Software Zen: delete this;

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                                • realJSOPR realJSOP

                                  My memory is failing. I copied some code to a thumb drive this morning intended to bring it to work, and left the damn thing at home. I do this a lot lately. A lot of times, I can't write code, leave it for more than a week, and be able to Pick up where I left off. I also find that I'm adding more comments to my code to help me remember what i was doing when I wrote it. I've also started commenting the hell outa my app.config files for the same reason (they often have more comments than settings). It sucks getting old...

                                  "Why don't you tie a kerosene-soaked rag around your ankles so the ants won't climb up and eat your candy ass..." - Dale Earnhardt, 1997
                                  -----
                                  "...the staggering layers of obscenity in your statement make it a work of art on so many levels." - Jason Jystad, 10/26/2001

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                                  Member 96
                                  wrote on last edited by
                                  #38

                                  I absolutely 100% believe this is entirely perception and not reality. When people get older they comment regularly on how they forget their keys or what to buy at the store or whatever. They call it senior moments etc. But take a look at any 20 year old, they do all the same stuff, they just don't think or worry about it. In them it's called being distracted or not paying attention or not focusing etc etc. As for code comments, I find my self doing that a *lot* more as well but the simple fact is that the complexity and size of the stuff I'm working on now is easily 100 times greater and my patience with sitting in front of the computer non-stop for 12 consecutive hours is out the window so I'm much more likely to take breaks, work on other things etc and this means I need more notes. Also, what I'm doing is never going to be as novel, new and interesting as it was at the start of my career. When something is new and interesting you remember it easily; when you've done it a million times and things just like it a million more it's easy for it to all wash together and be harder to bring back into mental focus when you step away from it. All the latest research on brain plasticity shows that there really is no limit to an undiseased brain at any age, a brain is always a "young" organ, it's just the weight of our experience that colours our perception of these things. I bet if you could have your memory wiped of all programming knowledge and just the interest left behind you'd find yourself coding just like you did when you first started in no time.


                                  "The pursuit of excellence is less profitable than the pursuit of bigness, but it can be more satisfying." - David Ogilvy

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                                  • A Anthony Mushrow

                                    Drugs, the solution to all of lifes problems. :rolleyes: Of course B12 isn't a drug in the usualy sense of the word.

                                    My current favourite word is: Bacon!

                                    -SK Genius

                                    Game Programming articles start -here[^]-

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                                    Douglas Troy
                                    wrote on last edited by
                                    #39

                                    SK Genius wrote:

                                    Drugs, the solution to all of lifes problems.

                                    I'm fairly certain the pharmaceutical companies are running a TV commercial that says that already ... :rolleyes:


                                    :..::. Douglas H. Troy ::..
                                    Bad Astronomy |VCF|wxWidgets|WTL

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                                    • realJSOPR realJSOP

                                      My memory is failing. I copied some code to a thumb drive this morning intended to bring it to work, and left the damn thing at home. I do this a lot lately. A lot of times, I can't write code, leave it for more than a week, and be able to Pick up where I left off. I also find that I'm adding more comments to my code to help me remember what i was doing when I wrote it. I've also started commenting the hell outa my app.config files for the same reason (they often have more comments than settings). It sucks getting old...

                                      "Why don't you tie a kerosene-soaked rag around your ankles so the ants won't climb up and eat your candy ass..." - Dale Earnhardt, 1997
                                      -----
                                      "...the staggering layers of obscenity in your statement make it a work of art on so many levels." - Jason Jystad, 10/26/2001

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                                      El Corazon
                                      wrote on last edited by
                                      #40

                                      John Simmons / outlaw programmer wrote:

                                      It sucks getting old...

                                      I am planning on doing a brain dump to Mustafa and worming my way into immortality. ;P

                                      _________________________ Asu no koto o ieba, tenjo de nezumi ga warau. Talk about things of tomorrow and the mice in the ceiling laugh. (Japanese Proverb) John Andrew Holmes "It is well to remember that the entire universe, with one trifling exception, is composed of others."

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                                      • realJSOPR realJSOP

                                        My memory is failing. I copied some code to a thumb drive this morning intended to bring it to work, and left the damn thing at home. I do this a lot lately. A lot of times, I can't write code, leave it for more than a week, and be able to Pick up where I left off. I also find that I'm adding more comments to my code to help me remember what i was doing when I wrote it. I've also started commenting the hell outa my app.config files for the same reason (they often have more comments than settings). It sucks getting old...

                                        "Why don't you tie a kerosene-soaked rag around your ankles so the ants won't climb up and eat your candy ass..." - Dale Earnhardt, 1997
                                        -----
                                        "...the staggering layers of obscenity in your statement make it a work of art on so many levels." - Jason Jystad, 10/26/2001

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                                        JimmyRopes
                                        wrote on last edited by
                                        #41

                                        John Simmons / outlaw programmer wrote:

                                        My memory is failing

                                        Memory is the second thing to go! :sigh:

                                        Simply Elegant Designs JimmyRopes Designs
                                        Think inside the box! ProActive Secure Systems
                                        I'm on-line therefore I am. JimmyRopes

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                                        • realJSOPR realJSOP

                                          I'm not interested in "injections". i think I'll just forget that you even mentioned it. :)

                                          "Why don't you tie a kerosene-soaked rag around your ankles so the ants won't climb up and eat your candy ass..." - Dale Earnhardt, 1997
                                          -----
                                          "...the staggering layers of obscenity in your statement make it a work of art on so many levels." - Jason Jystad, 10/26/2001

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                                          Tom Delany
                                          wrote on last edited by
                                          #42

                                          I thought it was just getting old for me. Maybe it is... but I recently found out I have severe sleep apnea, and that is most likely why I can never seem to concentrate any more. It's insidious. Sneaks up on you and you don't even realize you have it. I just thought stress, etc. were making me an insomniac. Hopefully I will see an improvement. How well do you sleep? Snore a lot? Wake up multiple times in the night for no reason? (I know... look, the dumb *** has something so now he thinks it is everybody's problem... :~)

                                          WE ARE DYSLEXIC OF BORG. Refutance is systile. Your a$$ will be laminated. There are 10 kinds of people in the world: People who know binary and people who don't.

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