Cancer Research
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Just wondering how everyone's going with their cancer research thingo's... My PC has been looking at 'superoxide dismutase' for 17 days now and I thought it was a pretty complex looking molecule, then along comes "VEGF Protein" as the target in the latest work unit... Man I'm glad I quit chemistry after high school and stuck to physics, that thing looks evil!! If you don't know what the hell I'm talking about (does everyone work on the same molecules at once, I wouldn't think so...) go look at the Nasty Protein :eek: Liam O'Hagan Senior Test Engineer GLI Australia www.gli.com.au
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Just wondering how everyone's going with their cancer research thingo's... My PC has been looking at 'superoxide dismutase' for 17 days now and I thought it was a pretty complex looking molecule, then along comes "VEGF Protein" as the target in the latest work unit... Man I'm glad I quit chemistry after high school and stuck to physics, that thing looks evil!! If you don't know what the hell I'm talking about (does everyone work on the same molecules at once, I wouldn't think so...) go look at the Nasty Protein :eek: Liam O'Hagan Senior Test Engineer GLI Australia www.gli.com.au
Looks like one of those bad 70's style slug monsters out of Dr Who :) cheers, Chris Maunder
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Just wondering how everyone's going with their cancer research thingo's... My PC has been looking at 'superoxide dismutase' for 17 days now and I thought it was a pretty complex looking molecule, then along comes "VEGF Protein" as the target in the latest work unit... Man I'm glad I quit chemistry after high school and stuck to physics, that thing looks evil!! If you don't know what the hell I'm talking about (does everyone work on the same molecules at once, I wouldn't think so...) go look at the Nasty Protein :eek: Liam O'Hagan Senior Test Engineer GLI Australia www.gli.com.au
That's the same one I've working on on all three boxes here. Funny thing is I don't even really understand what it is this program is actually doing and what exactly are "hits".
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That's the same one I've working on on all three boxes here. Funny thing is I don't even really understand what it is this program is actually doing and what exactly are "hits".
A "Hit" is used to describe a molecule which invokes (or surpressess) a biological response. In the case of this project, the hits are theoretical, based on interaction between the molecules atoms, and those of the protein. The next steps in the lab would be to synthesis the most promising of these hits, and squirt them into a solution of the protein, to check for the response. After that, if it satisfies a huge number of conditions (minor things like toxicity, and if it might make a profit or not) The best part of this project is that the large pharmas throw millions into computational chemistry, and they don't have anything like the power this project has harnessed. Up the Workers! Yours etc. Ex harrassed Drug researcher :mad:
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A "Hit" is used to describe a molecule which invokes (or surpressess) a biological response. In the case of this project, the hits are theoretical, based on interaction between the molecules atoms, and those of the protein. The next steps in the lab would be to synthesis the most promising of these hits, and squirt them into a solution of the protein, to check for the response. After that, if it satisfies a huge number of conditions (minor things like toxicity, and if it might make a profit or not) The best part of this project is that the large pharmas throw millions into computational chemistry, and they don't have anything like the power this project has harnessed. Up the Workers! Yours etc. Ex harrassed Drug researcher :mad:
Cool :) thanks for the clarificaton! I'm back on superoxide dismutase again.... Senior Test Engineer GLI Australia www.gli.com.au
