Yes. I have an old Windows 10 box loaded with several drives and using "storage spaces" to provide data duplication. I use it as a file server and backup device for several laptops and the wife's desktop. One advantage storage spaces has over RAID is that the drives don't have to be the same size. I think that Synology have a similar system on their latest 4 drive NAS's.

I've had no problems with Windows Home Server - it backs up everything each night. I've even restored a computer from it. It just seems to work...