have you put a break point in to check that the SelectionChanged Event is being triggered and passed through to the event handler? If you don't set the vivibility explicitly in the PageLoad is the combo box working as expected? I'm not able to reproduce your problem here at all from the information you have provided, so include the WPF where you decalre your combo box, page load event and at least one group box. also include the code for your selection chanage event handler and page load event handler. Or send me your project via email(my profile > right click homepage >copy link location) email address is there for a short while.