In general, no. The movement of the wheels has no effect on lift. To take flight, a craft needs either sufficient airflow across the wings or enough thrust to overcome gravity. A plane can take off from a stationary position, without a conveyor, if there is enough wind and the engine has enough thrust to counteract the drag; the plane would simply rise straight off the ground. Additionally, air craft with very powerful engines, like an F-16, can accelerate vertically. In this case, the wings do not generate lift; the engine itself provides all the lift. Theoretically, an F-16 could take off from a stationary but vertical position. Again, the wheels would not be used for this.

You're right. You only need 3 wires for duplex communication. Assuming you connected these wires correctly. the next question is what kind of cable are you using. Transmission lines cause reflections and energy loss. At 10 feet, your cable is long enough to be affected by it. If you're using 3 loose wires, that's a problem; try twisting the wires together. Ideally, you want 100 ohm impedance with 24 AWG wire. If you're using a pre-built cable, check the specs. It may be designed for something else. I also suggest you make sure both computers are powered from the same circuit; otherwise, you may have issues with ground loops.