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Genetics Question

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  • D Dirk Higbee

    Actually, our cells regenerate themselves every 7 years but doctors don't know why we age. One theory is, if you believe in God, as it says in the bible God set the age limit of man to 70-80 years because of all the wickedness in the world. Before that people were living to be 700-900 years old.

    If you can read, you can learn

    P Offline
    P Offline
    PIEBALDconsult
    wrote on last edited by
    #19

    justfunnin wrote:

    700-900 years old.

    I heard [citation needed] they may have counted months, not years.

    B 1 Reply Last reply
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    • M Mircea Grelus

      Seriously I'd contact those scientists that were able to regenerate that man's finger, let them know about my condition and see what they think. I've seen a video of theirs but haven't been able to find the link. They've also been able to create an esophagus using pig bladder as well, that when surgically implemented it forces the esophagus to regenerate onto itself.

      Cheers, Mircea "Pay people peanuts and you get monkeys" - David Ogilvy

      M Offline
      M Offline
      Member 96
      wrote on last edited by
      #20

      Mircea Grelus wrote:

      but haven't been able to find the link

      See my post in this thread


      Cum catapultae proscriptae erunt tum soli proscripti catapultas habebunt

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      • M martin_hughes

        Yeah you're right... I only type with two fingers anyway :) Still pisses me off that they won't regrow though. Stupid body.

        Me: Can you see the "up" arrow? User:Errr...ummm....no. Me: Can you see an arrow that points upwards? User: Oh yes, I see it now! -Excerpt from a support call taken by me, 08/31/2007

        L Offline
        L Offline
        l a u r e n
        wrote on last edited by
        #21

        i lost the sight in my right eye and was told it wouldnt come back even after they operated to stop me losing the sight in my left eye too ... i know the feelings you have ... i got my sight back (kinda a small miracle) but it made me understand a whole bunch of stuff in life differently :suss:

        "mostly watching the human race is like watching dogs watch tv ... they see the pictures move but the meaning escapes them"

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        • M Member 96

          Mircea Grelus wrote:

          but haven't been able to find the link

          See my post in this thread


          Cum catapultae proscriptae erunt tum soli proscripti catapultas habebunt

          M Offline
          M Offline
          Mircea Grelus
          wrote on last edited by
          #22

          Exactly. That's what I was looking for.

          Cheers, Mircea "Pay people peanuts and you get monkeys" - David Ogilvy

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          • M martin_hughes

            Why the hell can't the body re-generate parts? The code is all there, surely, so why is there no way to reboot it?

            Me: Can you see the "up" arrow? User:Errr...ummm....no. Me: Can you see an arrow that points upwards? User: Oh yes, I see it now! -Excerpt from a support call taken by me, 08/31/2007

            F Offline
            F Offline
            FyreWyrm
            wrote on last edited by
            #23

            Sorry to hear about your condition Martin. I had a great grandfather who had both of his legs amputated because of a nerve disorder similar to paralysis. I have a degree in genetics and during my classes we talked about this somewhat. The general concensus was humans cannot regenerate full body parts because of cell specialization. When a human embryo is forming, the cells being produced are general, all-purpose cells (stem cells). As the embryo grows the cells begin to specialize becoming nerve cells, muscle cells, bone cells, etc. Once the fetus reaches about the third trimester almost all of the stem cells have become specialized. The closest thing to a stem cell in a newborn is the proto-cells in bone marrow (which produce blood cells throughout our life). So the answer to your question in short, we can't regenerate because we don't have any general cells to form specialized cells from. There are few specialized cells in the body that can divide. Skin cells, liver cells, bone marrow cells, and cancer cells are the only ones that I can think of that can reproduce. Contrary to popular belief, muscle cells DO NOT divide. Does any of that make sense? As for the "why do we age" question: three words "Programmed Cell Death". Believe it or not, our DNA is actually designed to kill us. We get wrinkles and saggy skin because the collagen and elastin protiens in our skin (which keep it tight) break down over time and our skin cells are not programmed to replenish it. Our bodies age because the cells in our organs are not programmed to mass reproduce and renew themselves. The few types of cells we have that can replenish themselves have a mechanism in them so that they only reproduce a preset number of times. After that, they die. Programmed Cell Death. And that concludes today's lecture.

            M B 2 Replies Last reply
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            • L l a u r e n

              i lost the sight in my right eye and was told it wouldnt come back even after they operated to stop me losing the sight in my left eye too ... i know the feelings you have ... i got my sight back (kinda a small miracle) but it made me understand a whole bunch of stuff in life differently :suss:

              "mostly watching the human race is like watching dogs watch tv ... they see the pictures move but the meaning escapes them"

              M Offline
              M Offline
              martin_hughes
              wrote on last edited by
              #24

              What you had was much more scary... I'll have 8 fingers ( well, 6 and 2 thumbs) left; jeez if it was me loosing my site, well even Mrs Martin Hughes would show some sympathy :)

              Me: Can you see the "up" arrow? User:Errr...ummm....no. Me: Can you see an arrow that points upwards? User: Oh yes, I see it now! -Excerpt from a support call taken by me, 08/31/2007

              L 1 Reply Last reply
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              • M martin_hughes

                What you had was much more scary... I'll have 8 fingers ( well, 6 and 2 thumbs) left; jeez if it was me loosing my site, well even Mrs Martin Hughes would show some sympathy :)

                Me: Can you see the "up" arrow? User:Errr...ummm....no. Me: Can you see an arrow that points upwards? User: Oh yes, I see it now! -Excerpt from a support call taken by me, 08/31/2007

                L Offline
                L Offline
                l a u r e n
                wrote on last edited by
                #25

                yeah ... heh ... all i was trying to say is it could be worse so while it definitely does suck eggs it could be worse so instead of focusing on the downsides (which we all do) i try to look at it as if i was coming from a place where what i have to deal with is good ... suppose they had originally said "you are going to lose your whole arm" but then a few days later had said "we think you will only lose two fingers" ... same place but different perception makes all the difference imho :)

                "mostly watching the human race is like watching dogs watch tv ... they see the pictures move but the meaning escapes them"

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                • F FyreWyrm

                  Sorry to hear about your condition Martin. I had a great grandfather who had both of his legs amputated because of a nerve disorder similar to paralysis. I have a degree in genetics and during my classes we talked about this somewhat. The general concensus was humans cannot regenerate full body parts because of cell specialization. When a human embryo is forming, the cells being produced are general, all-purpose cells (stem cells). As the embryo grows the cells begin to specialize becoming nerve cells, muscle cells, bone cells, etc. Once the fetus reaches about the third trimester almost all of the stem cells have become specialized. The closest thing to a stem cell in a newborn is the proto-cells in bone marrow (which produce blood cells throughout our life). So the answer to your question in short, we can't regenerate because we don't have any general cells to form specialized cells from. There are few specialized cells in the body that can divide. Skin cells, liver cells, bone marrow cells, and cancer cells are the only ones that I can think of that can reproduce. Contrary to popular belief, muscle cells DO NOT divide. Does any of that make sense? As for the "why do we age" question: three words "Programmed Cell Death". Believe it or not, our DNA is actually designed to kill us. We get wrinkles and saggy skin because the collagen and elastin protiens in our skin (which keep it tight) break down over time and our skin cells are not programmed to replenish it. Our bodies age because the cells in our organs are not programmed to mass reproduce and renew themselves. The few types of cells we have that can replenish themselves have a mechanism in them so that they only reproduce a preset number of times. After that, they die. Programmed Cell Death. And that concludes today's lecture.

                  M Offline
                  M Offline
                  martin_hughes
                  wrote on last edited by
                  #26

                  FyreWyrm wrote:

                  Does any of that make sense?

                  Nope!

                  FyreWyrm wrote:

                  As for the "why do we age" question: three words "Programmed Cell Death". Believe it or not, our DNA is actually designed to kill us. We get wrinkles and saggy skin because the collagen and elastin protiens in our skin (which keep it tight) break down over time and our skin cells are not programmed to replenish it.

                  Can we ever reboot the human genome? I mean that my DNA (or so I am told) describes my physical form completely, is there anything can cause what's missing to reappear? (Actually, I heard this happen in reptiles... so why not us?)

                  Me: Can you see the "up" arrow? User:Errr...ummm....no. Me: Can you see an arrow that points upwards? User: Oh yes, I see it now! -Excerpt from a support call taken by me, 08/31/2007

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                  • M martin_hughes

                    Why the hell can't the body re-generate parts? The code is all there, surely, so why is there no way to reboot it?

                    Me: Can you see the "up" arrow? User:Errr...ummm....no. Me: Can you see an arrow that points upwards? User: Oh yes, I see it now! -Excerpt from a support call taken by me, 08/31/2007

                    E Offline
                    E Offline
                    El Corazon
                    wrote on last edited by
                    #27

                    martin_hughes wrote:

                    Why the hell can't the body re-generate parts? The code is all there, surely, so why is there no way to reboot it?

                    I have written several replies, throwing each away. This is a tough question because I don't have any answers either. I know people are working for them, I even know a few of them. My situation is minor compared to you, I only lost a pancrease, and about 20 years. The latter I might gain back through hard work, but no way to know for sure. My wife would shoot me if I told her situation, but she's got both us beat. All we can do is keep plodding along and doing our part. I am still here, and that is a darned sure better thing than it could've been. Since my infection I have done side work with medical visualization because it is the only thing I can do to help. Small as it is, maybe there is some young kid with the answers that just needs a way to see the data right. That much, maybe I can help with. Well, and it keeps me going, and positive for both mine, and my wife's situation. And maybe yours as well. I don't know how to regenerate organs, or any other body parts. I know graphics, and I will do graphics until I fall over. :) I'm a lousy pep-talker, so I won't try. I was pretty damn depressed when the doctors explained just how much I have lost. But that was the past. Tomorrow? who knows? we might just get it back. I can hope at least.

                    _________________________ Asu no koto o ieba, tenjo de nezumi ga warau. Talk about things of tomorrow and the mice in the ceiling laugh. (Japanese Proverb)

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                    • M martin_hughes

                      FyreWyrm wrote:

                      Does any of that make sense?

                      Nope!

                      FyreWyrm wrote:

                      As for the "why do we age" question: three words "Programmed Cell Death". Believe it or not, our DNA is actually designed to kill us. We get wrinkles and saggy skin because the collagen and elastin protiens in our skin (which keep it tight) break down over time and our skin cells are not programmed to replenish it.

                      Can we ever reboot the human genome? I mean that my DNA (or so I am told) describes my physical form completely, is there anything can cause what's missing to reappear? (Actually, I heard this happen in reptiles... so why not us?)

                      Me: Can you see the "up" arrow? User:Errr...ummm....no. Me: Can you see an arrow that points upwards? User: Oh yes, I see it now! -Excerpt from a support call taken by me, 08/31/2007

                      F Offline
                      F Offline
                      FyreWyrm
                      wrote on last edited by
                      #28

                      martin_hughes wrote:

                      is there anything can cause what's missing to reappear?

                      That's one of the questions stem cell research was trying to answer. You can thank the US government for ending that quest.

                      S 1 Reply Last reply
                      0
                      • L l a u r e n

                        yeah ... heh ... all i was trying to say is it could be worse so while it definitely does suck eggs it could be worse so instead of focusing on the downsides (which we all do) i try to look at it as if i was coming from a place where what i have to deal with is good ... suppose they had originally said "you are going to lose your whole arm" but then a few days later had said "we think you will only lose two fingers" ... same place but different perception makes all the difference imho :)

                        "mostly watching the human race is like watching dogs watch tv ... they see the pictures move but the meaning escapes them"

                        M Offline
                        M Offline
                        martin_hughes
                        wrote on last edited by
                        #29

                        You're an angel, and don't ever tell Mrs MH I said that :)

                        Me: Can you see the "up" arrow? User:Errr...ummm....no. Me: Can you see an arrow that points upwards? User: Oh yes, I see it now! -Excerpt from a support call taken by me, 08/31/2007

                        L 1 Reply Last reply
                        0
                        • E El Corazon

                          martin_hughes wrote:

                          Why the hell can't the body re-generate parts? The code is all there, surely, so why is there no way to reboot it?

                          I have written several replies, throwing each away. This is a tough question because I don't have any answers either. I know people are working for them, I even know a few of them. My situation is minor compared to you, I only lost a pancrease, and about 20 years. The latter I might gain back through hard work, but no way to know for sure. My wife would shoot me if I told her situation, but she's got both us beat. All we can do is keep plodding along and doing our part. I am still here, and that is a darned sure better thing than it could've been. Since my infection I have done side work with medical visualization because it is the only thing I can do to help. Small as it is, maybe there is some young kid with the answers that just needs a way to see the data right. That much, maybe I can help with. Well, and it keeps me going, and positive for both mine, and my wife's situation. And maybe yours as well. I don't know how to regenerate organs, or any other body parts. I know graphics, and I will do graphics until I fall over. :) I'm a lousy pep-talker, so I won't try. I was pretty damn depressed when the doctors explained just how much I have lost. But that was the past. Tomorrow? who knows? we might just get it back. I can hope at least.

                          _________________________ Asu no koto o ieba, tenjo de nezumi ga warau. Talk about things of tomorrow and the mice in the ceiling laugh. (Japanese Proverb)

                          M Offline
                          M Offline
                          martin_hughes
                          wrote on last edited by
                          #30

                          Do you know what I hate most about it all? My darling wife goes through it all with me. That and I've suddenly started liking Fleetwood Mac's "Everywhere". :) I think when they're gone I'll hate Fleetwood Mac, if Mrs. MH will let me - she's my rock. I wish I were with her now instead of 300 miles away on business; but given she'd probably hit me for expressing such sentiments.... maybe not :)

                          Me: Can you see the "up" arrow? User:Errr...ummm....no. Me: Can you see an arrow that points upwards? User: Oh yes, I see it now! -Excerpt from a support call taken by me, 08/31/2007

                          E 1 Reply Last reply
                          0
                          • M martin_hughes

                            Do you know what I hate most about it all? My darling wife goes through it all with me. That and I've suddenly started liking Fleetwood Mac's "Everywhere". :) I think when they're gone I'll hate Fleetwood Mac, if Mrs. MH will let me - she's my rock. I wish I were with her now instead of 300 miles away on business; but given she'd probably hit me for expressing such sentiments.... maybe not :)

                            Me: Can you see the "up" arrow? User:Errr...ummm....no. Me: Can you see an arrow that points upwards? User: Oh yes, I see it now! -Excerpt from a support call taken by me, 08/31/2007

                            E Offline
                            E Offline
                            El Corazon
                            wrote on last edited by
                            #31

                            martin_hughes wrote:

                            but given she'd probably hit me for expressing such sentiments.... maybe not

                            hopefully not. I think back on my problems, I spent 2 months in the hospital, and then I find out my wife (now, not then) checked herself out of the hospital 48 hours after her surgery. Damn, that's a gutsy woman. She keeps me positive too. Heck, if she can do that, I've got it easy!

                            _________________________ Asu no koto o ieba, tenjo de nezumi ga warau. Talk about things of tomorrow and the mice in the ceiling laugh. (Japanese Proverb)

                            1 Reply Last reply
                            0
                            • F FyreWyrm

                              martin_hughes wrote:

                              is there anything can cause what's missing to reappear?

                              That's one of the questions stem cell research was trying to answer. You can thank the US government for ending that quest.

                              S Offline
                              S Offline
                              Shog9 0
                              wrote on last edited by
                              #32

                              FyreWyrm wrote:

                              You can thank the US government for ending that quest.

                              Or you can donate your own money to fund research. You know. Whatever you think'll be more productive.

                              every night, i kneel at the foot of my bed and thank the Great Overseeing Politicians for protecting my freedoms by reducing their number, as if they were deer in a state park. -- Chris Losinger, Online Poker Players?

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                              • M Marc Clifton

                                Mircea Grelus wrote:

                                It regenerates blood cells, skin, bones,

                                The liver too. It's an interesting thing--you can remove half a person's liver and it will regenerate. Quite painful, I hear though. Marc

                                Thyme In The Country
                                Interacx
                                My Blog

                                B Offline
                                B Offline
                                Brady Kelly
                                wrote on last edited by
                                #33

                                Yes, a friend of mine had more than half hers removed, and she said the pain was unbelievable. Only pethidine made it just bearable.

                                MY BLOG

                                1 Reply Last reply
                                0
                                • C Christian Graus

                                  I guess the other question is, why do we age ? The answer probably is, if we were indestructable, and we could still breed, the world would have been overpopulated a long time ago.

                                  Christian Graus - Microsoft MVP - C++ "also I don't think "TranslateOneToTwoBillion OneHundredAndFortySevenMillion FourHundredAndEightyThreeThousand SixHundredAndFortySeven()" is a very good choice for a function name" - SpacixOne ( offering help to someone who really needed it ) ( spaces added for the benefit of people running at < 1280x1024 )

                                  B Offline
                                  B Offline
                                  Brady Kelly
                                  wrote on last edited by
                                  #34

                                  That hints at a belief in design over evolution. If we diodn't age, we might well have been overpopulated, but it would introduce other reasons for not living very long, rather than aging. Ageing is cause by an imperfect copying DNA process during cell division, with defects slowly creeping into successive generations of cells.

                                  MY BLOG

                                  1 Reply Last reply
                                  0
                                  • P PIEBALDconsult

                                    justfunnin wrote:

                                    700-900 years old.

                                    I heard [citation needed] they may have counted months, not years.

                                    B Offline
                                    B Offline
                                    Brady Kelly
                                    wrote on last edited by
                                    #35

                                    My father believes the literal interpretation, although acknowledges the years weren't exactly our twelve Gregorian months. His school believes several factors have resulted in an ever diminishing life span, starting with the fall, then the flood which separated water in the heavens, which provided serious cloud cover and protection from UV, to water on Earth, and the consequence of the fall that man was forced to begin eating flesh to survive after losing the guaranteed food supply of Eden. The narrow gene pool implied by the creationist argument is also held partly responsible for shortening lifespans.

                                    MY BLOG

                                    1 Reply Last reply
                                    0
                                    • F FyreWyrm

                                      Sorry to hear about your condition Martin. I had a great grandfather who had both of his legs amputated because of a nerve disorder similar to paralysis. I have a degree in genetics and during my classes we talked about this somewhat. The general concensus was humans cannot regenerate full body parts because of cell specialization. When a human embryo is forming, the cells being produced are general, all-purpose cells (stem cells). As the embryo grows the cells begin to specialize becoming nerve cells, muscle cells, bone cells, etc. Once the fetus reaches about the third trimester almost all of the stem cells have become specialized. The closest thing to a stem cell in a newborn is the proto-cells in bone marrow (which produce blood cells throughout our life). So the answer to your question in short, we can't regenerate because we don't have any general cells to form specialized cells from. There are few specialized cells in the body that can divide. Skin cells, liver cells, bone marrow cells, and cancer cells are the only ones that I can think of that can reproduce. Contrary to popular belief, muscle cells DO NOT divide. Does any of that make sense? As for the "why do we age" question: three words "Programmed Cell Death". Believe it or not, our DNA is actually designed to kill us. We get wrinkles and saggy skin because the collagen and elastin protiens in our skin (which keep it tight) break down over time and our skin cells are not programmed to replenish it. Our bodies age because the cells in our organs are not programmed to mass reproduce and renew themselves. The few types of cells we have that can replenish themselves have a mechanism in them so that they only reproduce a preset number of times. After that, they die. Programmed Cell Death. And that concludes today's lecture.

                                      B Offline
                                      B Offline
                                      Brady Kelly
                                      wrote on last edited by
                                      #36

                                      FyreWyrm wrote:

                                      DNA is actually designed to kill us

                                      Is that an ID theory, or does your 'programming' evolve due to random mutations?

                                      MY BLOG

                                      E 1 Reply Last reply
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                                      • M martin_hughes

                                        You're an angel, and don't ever tell Mrs MH I said that :)

                                        Me: Can you see the "up" arrow? User:Errr...ummm....no. Me: Can you see an arrow that points upwards? User: Oh yes, I see it now! -Excerpt from a support call taken by me, 08/31/2007

                                        L Offline
                                        L Offline
                                        l a u r e n
                                        wrote on last edited by
                                        #37

                                        :)

                                        "mostly watching the human race is like watching dogs watch tv ... they see the pictures move but the meaning escapes them"

                                        1 Reply Last reply
                                        0
                                        • D Dirk Higbee

                                          Actually, our cells regenerate themselves every 7 years but doctors don't know why we age. One theory is, if you believe in God, as it says in the bible God set the age limit of man to 70-80 years because of all the wickedness in the world. Before that people were living to be 700-900 years old.

                                          If you can read, you can learn

                                          H Offline
                                          H Offline
                                          hairy_hats
                                          wrote on last edited by
                                          #38

                                          justfunnin wrote:

                                          Actually, our cells regenerate themselves every 7 years but doctors don't know why we age.

                                          The telomeres protecting the ends of our DNA get shorter with every cell division, so there is a limit to the number of times the cells can be regenerated without DNA damage increasing.

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