DNA sequencing
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I am a curious amateur, knowing "nothing" about advanced biology. But I am curious :-) I still remember the days when there was a race to be the first research institute to do a complete sequencing of human DNA. It took weeks, or maybe it was months. Nowadays, DNA sequencing seems to be as simple as taking a breath. "Everyone" seems to do it in a snap. Covid19 RNA (it is RNA, isn't it? or is it DNA?) is obviously magnitudes below human DNA, but even human DNA sequencing seems to be a piece of cake today, to determine your ancestry, or your disposition of various diseases, or in criminal cases, or for a whole lot of other purposes. Most of this change has come in less than twenty years. What happened? Computers haven't become that much faster! (I got the impression that they are essential as a tool.) Is the speedup in other, non-computer analysis hardware? Or have the scientists developed a completely new methodology that is a magnitude or two faster? Or are those companies offering info about ancestry or disease risk doing only a quick, partial analysis rather than a full sequencing? To phrase it differently: If we twenty years ago had had all the knowledge that we have today about methodologies, would the hardware of the day be capable of sequencing the human genome in a many hours as they did use months, or are the methods of today fully dependent on recent hardware development? (I assume that computer hardware development is only part of it!)
Nowadays you can buy an affordable DNA sequencer on alibaba or even make it by yourself :cool: You can even play with gene modification at home. Guess what's the next generation of script kiddies is going to be ;)
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There is no "both sides of the issue" with this. There are the people who accept the word of experts and doctors on virus behavior and its impact on society, and then the people who deny the reality of it, thinking they know more than the people who study this stuff for their entire lives. You either know what Dunning-Kruger is, or you're on the low end of that spectrum.
Asking questions is a skill CodeProject Forum Guidelines Google: C# How to debug code Seriously, go read these articles.
Dave KreskowiakDave Kreskowiak wrote:
There is no "both sides of the issue" with this.
Really?
Dave Kreskowiak wrote:
There are the people who accept the word of experts and doctors on virus behavior and its impact on society,
That's one side.
Dave Kreskowiak wrote:
and then the people who deny the reality of it
And that looks like another side. :laugh:
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Imagine the same with polio. Look up what the disease did, and how vaccines killed it. There's no discussion here.
Bastard Programmer from Hell :suss: "If you just follow the bacon Eddy, wherever it leads you, then you won't have to think about politics." -- Some Bell.
Eddy Vluggen wrote:
Imagine the same with polio.
Polio and covid cannot be compared this way.
Eddy Vluggen wrote:
There's no discussion here.
Yes, I am seeing that pattern with you. My only point was that you call people who think Covid is not as bad as you do idiots, and they call you an idiot. Possibly both sides are right. :laugh:
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Then quit reading and responding to what he writes.
The Science of King David's Court | Object Oriented Programming with C++
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You sure told him. :laugh:
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Eddy Vluggen wrote:
Imagine the same with polio.
Polio and covid cannot be compared this way.
Eddy Vluggen wrote:
There's no discussion here.
Yes, I am seeing that pattern with you. My only point was that you call people who think Covid is not as bad as you do idiots, and they call you an idiot. Possibly both sides are right. :laugh:
20212 wrote:
Possibly both sides are right. :laugh:
Sorry, Spanky. Deadly diseases do not behave like Schroedinger's Cat
"The difference between genius and stupidity is that genius has its limits." - Albert Einstein
"If you are searching for perfection in others, then you seek disappointment. If you seek perfection in yourself, then you will find failure." - Balboos HaGadol Mar 2010
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So, you trouble with history? We could and we won't. Because in time of polio, everyone wanted vaccine.
Slacker007 wrote:
I say we wear masks forever, and stay in lockdown forever.
That's what I expect; if people do not want vaccine nor stick to the rules, the virus will spread, and with spreading it will copy a million times in every new body. And thus, it will evolve faster. And with part of us vaccinated it will evolve beyond that. If just part of us vaccinated and lot infected, it will mutate beyond that. There once was a time where we celebrated new vaccines because they save lives. Congratulations and kudo's to you.
Bastard Programmer from Hell :suss: "If you just follow the bacon Eddy, wherever it leads you, then you won't have to think about politics." -- Some Bell.
Even back when we had a soapbox, when he found himself shyte-faced, his answer was just his often-used hiding place of being dismissive. To a varying (but considerable) degrees, it's the cult/conspiracy mentality. Anything that contradicts the dogma is party to the conspiracy and thus dismissed - eyes wired closed. Or, for some who think they've not been totally indoctrinated, they just try to ridicule what they don't agree with, then believe their own evasive position as being some equivalence of proof. If you look not only in the US, but throughout the world, COVID isn't the only deadly disease going around - the likely more dangerous one is in heads (and I don't mean a head-cold).
"The difference between genius and stupidity is that genius has its limits." - Albert Einstein
"If you are searching for perfection in others, then you seek disappointment. If you seek perfection in yourself, then you will find failure." - Balboos HaGadol Mar 2010
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20212 wrote:
Possibly both sides are right. :laugh:
Sorry, Spanky. Deadly diseases do not behave like Schroedinger's Cat
"The difference between genius and stupidity is that genius has its limits." - Albert Einstein
"If you are searching for perfection in others, then you seek disappointment. If you seek perfection in yourself, then you will find failure." - Balboos HaGadol Mar 2010
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Dave Kreskowiak wrote:
There is no "both sides of the issue" with this.
Really?
Dave Kreskowiak wrote:
There are the people who accept the word of experts and doctors on virus behavior and its impact on society,
That's one side.
Dave Kreskowiak wrote:
and then the people who deny the reality of it
And that looks like another side. :laugh:
Oh, you misunderstand. When I hear "two sides of an issue", that means there's discussion with some semblance of rational thought on both sides. This issue, no. There's one side that just denies reality, listens to the right-wing marketing, and has no rational thought process justifying their position.
Asking questions is a skill CodeProject Forum Guidelines Google: C# How to debug code Seriously, go read these articles.
Dave Kreskowiak -
Oh, you misunderstand. When I hear "two sides of an issue", that means there's discussion with some semblance of rational thought on both sides. This issue, no. There's one side that just denies reality, listens to the right-wing marketing, and has no rational thought process justifying their position.
Asking questions is a skill CodeProject Forum Guidelines Google: C# How to debug code Seriously, go read these articles.
Dave KreskowiakDave Kreskowiak wrote:
denies reality,
What reality? The one where we were told millions would die last year? Or the reality that masks are good, or wait, they don't help much, or wait they're essential, or wait, not so much, or wait, they are mandatory? That reality?
Dave Kreskowiak wrote:
right-wing marketing
What benefit or motive does the right-wing have to be against vaccines? Or what are you suggesting the right-wing is denying? I know lot's of right-wingers and nearly all of them want the vaccine. You are claiming right-wing craziness but without some explanation you sound like a left-wing screamer with no facts. Can you expand on what you mean?
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Dave Kreskowiak wrote:
denies reality,
What reality? The one where we were told millions would die last year? Or the reality that masks are good, or wait, they don't help much, or wait they're essential, or wait, not so much, or wait, they are mandatory? That reality?
Dave Kreskowiak wrote:
right-wing marketing
What benefit or motive does the right-wing have to be against vaccines? Or what are you suggesting the right-wing is denying? I know lot's of right-wingers and nearly all of them want the vaccine. You are claiming right-wing craziness but without some explanation you sound like a left-wing screamer with no facts. Can you expand on what you mean?
Oh, really? How about every red state treating this like the common cold? Never shutting down, or, now, opening up way too early with no mask mandates? The Republican mantra is "Profit at all costs". Opening up and freely letting the virus spread will only do two things. Kill more people and give the virus more and more opportunity to mutate, possibly into something the current vaccines cannot protect against. All so businesses can survive over people surviving. Texas has 7% of its population vaccinated and is opening up 100% next week like there's no chance of anyone getting infected.
Asking questions is a skill CodeProject Forum Guidelines Google: C# How to debug code Seriously, go read these articles.
Dave Kreskowiak -
Dave Kreskowiak wrote:
denies reality,
What reality? The one where we were told millions would die last year? Or the reality that masks are good, or wait, they don't help much, or wait they're essential, or wait, not so much, or wait, they are mandatory? That reality?
Dave Kreskowiak wrote:
right-wing marketing
What benefit or motive does the right-wing have to be against vaccines? Or what are you suggesting the right-wing is denying? I know lot's of right-wingers and nearly all of them want the vaccine. You are claiming right-wing craziness but without some explanation you sound like a left-wing screamer with no facts. Can you expand on what you mean?
20212 wrote:
The one where we were told millions would die last year?
You apparently didn't listen to the entire speech, or just got your information from some right-wing "news" site. It was pointed with "if we did nothing at all to control the spread".
Quote:
masks are good, or wait, they don't help much, or wait they're essential, or wait, not so much, or wait, they are mandatory
The only side that was spouting that crap was right-wing sources. And if you had any doubts or were confused, the correct default position would be to error on the side of caution and mask up. The whole point of masks (and this has never changed!) is to prevent from spread FROM YOU, TO OTHERS.
Asking questions is a skill CodeProject Forum Guidelines Google: C# How to debug code Seriously, go read these articles.
Dave Kreskowiak -
Oh, really? How about every red state treating this like the common cold? Never shutting down, or, now, opening up way too early with no mask mandates? The Republican mantra is "Profit at all costs". Opening up and freely letting the virus spread will only do two things. Kill more people and give the virus more and more opportunity to mutate, possibly into something the current vaccines cannot protect against. All so businesses can survive over people surviving. Texas has 7% of its population vaccinated and is opening up 100% next week like there's no chance of anyone getting infected.
Asking questions is a skill CodeProject Forum Guidelines Google: C# How to debug code Seriously, go read these articles.
Dave KreskowiakDave Kreskowiak wrote:
How about every red state treating this like the common cold? Never shutting down, or, now, opening up way too early with no mask mandates?
I do find it interesting that how people see this virus tends to be the same as others in their political party. I hope someone does a serious study on that. I do find that interesting. Your language is a bit over the top, in my opinion. No one is treating it like a common cold. Every state has had shutdowns and that has never happened for the cold, but I believe I get your point even through the hyperbole. Where I live, schools opened up in August 5 days a week and there have been no major issues. I have gone to the movie theaters and not had a problem. One of my kids works at a grocery store and has been in public since day one. We have gotten the virus but it was not big deal. Other people at my work have gotten it and recovered quickly. My point is, from everything I experience I can see that the virus is not as big of a deal as others are making it. Of course, that is not to say that some have not been impacted greatly. So, there are 2 sides. One side that thinks Covid is severe enough to shut everything down and hide until it is gone. And there might be some science to back that up. And then there is the other side, those that have actual experience (the best kind of science possible) to say that we can get back to normal and still be fine overall. Neither side is denying science. Both sides are picking the science that makes them feel more comfortable. But all this talk of the other side being idiots or denying science is just nonsense.
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20212 wrote:
The one where we were told millions would die last year?
You apparently didn't listen to the entire speech, or just got your information from some right-wing "news" site. It was pointed with "if we did nothing at all to control the spread".
Quote:
masks are good, or wait, they don't help much, or wait they're essential, or wait, not so much, or wait, they are mandatory
The only side that was spouting that crap was right-wing sources. And if you had any doubts or were confused, the correct default position would be to error on the side of caution and mask up. The whole point of masks (and this has never changed!) is to prevent from spread FROM YOU, TO OTHERS.
Asking questions is a skill CodeProject Forum Guidelines Google: C# How to debug code Seriously, go read these articles.
Dave KreskowiakDave Kreskowiak wrote:
listen to the entire speech, or just got your information from some right-wing "news" site. It was pointed with "if we did nothing at all to control the spread".
No, because this was after Trump had already started doing things. There was never any "if we do nothing." Remember, he shut down travel to and from China and Biden called him a xenophobe? And then later towards election time Biden kept claiming Trump didn't react quickly enough? :laugh: Anyway, let politics stay in politics.
Dave Kreskowiak wrote:
The only side that was spouting that crap was right-wing sources.
Dr. Fauci and the CDC are right wing?
Dave Kreskowiak wrote:
The whole point of masks (and this has never changed!) is to prevent from spread FROM YOU, TO OTHERS.
Yes, and?
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Dave Kreskowiak wrote:
How about every red state treating this like the common cold? Never shutting down, or, now, opening up way too early with no mask mandates?
I do find it interesting that how people see this virus tends to be the same as others in their political party. I hope someone does a serious study on that. I do find that interesting. Your language is a bit over the top, in my opinion. No one is treating it like a common cold. Every state has had shutdowns and that has never happened for the cold, but I believe I get your point even through the hyperbole. Where I live, schools opened up in August 5 days a week and there have been no major issues. I have gone to the movie theaters and not had a problem. One of my kids works at a grocery store and has been in public since day one. We have gotten the virus but it was not big deal. Other people at my work have gotten it and recovered quickly. My point is, from everything I experience I can see that the virus is not as big of a deal as others are making it. Of course, that is not to say that some have not been impacted greatly. So, there are 2 sides. One side that thinks Covid is severe enough to shut everything down and hide until it is gone. And there might be some science to back that up. And then there is the other side, those that have actual experience (the best kind of science possible) to say that we can get back to normal and still be fine overall. Neither side is denying science. Both sides are picking the science that makes them feel more comfortable. But all this talk of the other side being idiots or denying science is just nonsense.
20212 wrote:
Your language is a bit over the top, in my opinion. No one is treating it like a common cold.
A bit over the top? What's more "over the top"? My language or 516,000+ dead because "it's only the flu", which is STILL circulating in right-wing circles to this day.
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Where I live, schools opened up in August 5 days a week and there have been no major issues. I have gone to the movie theaters and not had a problem. One of my kids works at a grocery store and has been in public since day one. We have gotten the virus but it was not big deal. Other people at my work have gotten it and recovered quickly. My point is, from everything I experience I can see that the virus is not as big of a deal as others are making it.
Oh look, more anecdotes that mean nothing on the larger scale, but make YOU feel better because it didn't directly impact YOU. If that's how you're going to play it, let me drop my anecdotes on you. In my social circles, 12 infected with 4 dead. My parents (in the age group with the highest mortality rate) got it from a couple of guys who had to be brought in for a plumbing problem that couldn't wait. My parents survived, but that was a scary couple of weeks.
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Neither side is denying science.
Bullshit. One side is listening to experts and the other is picking and choosing, based on what you just did, throwing anecdotes around. "It didn't directly impact me or it wasn't so bad for me, so it isn't as bad as they are saying."
Asking questions is a skill CodeProject Forum Guidelines Google: C# How to debug code Seriously, go read these articles.
Dave Kreskowiak -
20212 wrote:
Your language is a bit over the top, in my opinion. No one is treating it like a common cold.
A bit over the top? What's more "over the top"? My language or 516,000+ dead because "it's only the flu", which is STILL circulating in right-wing circles to this day.
Quote:
Where I live, schools opened up in August 5 days a week and there have been no major issues. I have gone to the movie theaters and not had a problem. One of my kids works at a grocery store and has been in public since day one. We have gotten the virus but it was not big deal. Other people at my work have gotten it and recovered quickly. My point is, from everything I experience I can see that the virus is not as big of a deal as others are making it.
Oh look, more anecdotes that mean nothing on the larger scale, but make YOU feel better because it didn't directly impact YOU. If that's how you're going to play it, let me drop my anecdotes on you. In my social circles, 12 infected with 4 dead. My parents (in the age group with the highest mortality rate) got it from a couple of guys who had to be brought in for a plumbing problem that couldn't wait. My parents survived, but that was a scary couple of weeks.
Quote:
Neither side is denying science.
Bullshit. One side is listening to experts and the other is picking and choosing, based on what you just did, throwing anecdotes around. "It didn't directly impact me or it wasn't so bad for me, so it isn't as bad as they are saying."
Asking questions is a skill CodeProject Forum Guidelines Google: C# How to debug code Seriously, go read these articles.
Dave KreskowiakDave Kreskowiak wrote:
"It didn't directly impact me or it wasn't so bad for me, so it isn't as bad as they are saying."
I specifically did not say that so either you are being way too emotional or dishonest. I'd love to have a civil conversation but you seem to be taking this too emotional. Sorry for the experiences you have had. But that does not diminish my experiences, and as I already stated, nor do my experiences diminish yours. Have a good day.
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Dave Kreskowiak wrote:
listen to the entire speech, or just got your information from some right-wing "news" site. It was pointed with "if we did nothing at all to control the spread".
No, because this was after Trump had already started doing things. There was never any "if we do nothing." Remember, he shut down travel to and from China and Biden called him a xenophobe? And then later towards election time Biden kept claiming Trump didn't react quickly enough? :laugh: Anyway, let politics stay in politics.
Dave Kreskowiak wrote:
The only side that was spouting that crap was right-wing sources.
Dr. Fauci and the CDC are right wing?
Dave Kreskowiak wrote:
The whole point of masks (and this has never changed!) is to prevent from spread FROM YOU, TO OTHERS.
Yes, and?
Quote:
There was never any "if we do nothing."
In the data coming from the experts, yes there was. Trump shutdown travel from China that took effect Jan 31st, but that didn't shutdown travel from China. The ban only impacted non-US citizens who had been in China in the last 2 weeks. It also didn't apply to immediate family of US citizens. We still had 380,000 people come in from China after that date, according to US Commerce data.
20212 wrote:
Dr. Fauci and the CDC are right wing?
Dave Kreskowiak wrote:
The whole point of masks (and this has never changed!) is to prevent from spread FROM YOU, TO OTHERS.
Yes, and?
Funny, I never heard from Fauci that masks don't work. I only hear that from the right-wing.
Asking questions is a skill CodeProject Forum Guidelines Google: C# How to debug code Seriously, go read these articles.
Dave Kreskowiak -
Dave Kreskowiak wrote:
"It didn't directly impact me or it wasn't so bad for me, so it isn't as bad as they are saying."
I specifically did not say that so either you are being way too emotional or dishonest. I'd love to have a civil conversation but you seem to be taking this too emotional. Sorry for the experiences you have had. But that does not diminish my experiences, and as I already stated, nor do my experiences diminish yours. Have a good day.
Ahem,
Quote:
My point is, from everything I experience I can see that the virus is not as big of a deal as others are making it.
Have a nice life.
Asking questions is a skill CodeProject Forum Guidelines Google: C# How to debug code Seriously, go read these articles.
Dave Kreskowiak -
Maybe I have understood it completely wrong, but I think he was backing you up as his message is for 20212's answer to your first comment. As I already have said a couple of times... try to take it easy Eddy, you are not being "attacked" by the whole CP
M.D.V. ;) If something has a solution... Why do we have to worry about?. If it has no solution... For what reason do we have to worry about? Help me to understand what I'm saying, and I'll explain it better to you Rating helpful answers is nice, but saying thanks can be even nicer.
Nelek wrote:
As I already have said a couple of times... try to take it easy Eddy, you are not being "attacked" by the whole CP
You're right, ofcourse. Been offered the advice before. Will try to take it more serious.
Bastard Programmer from Hell :suss: "If you just follow the bacon Eddy, wherever it leads you, then you won't have to think about politics." -- Some Bell.
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Eddy Vluggen wrote:
Imagine the same with polio.
Polio and covid cannot be compared this way.
Eddy Vluggen wrote:
There's no discussion here.
Yes, I am seeing that pattern with you. My only point was that you call people who think Covid is not as bad as you do idiots, and they call you an idiot. Possibly both sides are right. :laugh:
20212a wrote:
Polio and covid cannot be compared this way.
Why not?
20212a wrote:
Yes, I am seeing that pattern with you.
So, this ad hominem is invalidating the statement how?
20212a wrote:
My only point was that you call people who think Covid is not as bad as you do idiots
You maid multiple "points". And yes, they're idiots; when was the last time all countries closed their borders? You are implying that's done all around the world for something that may be harmless. That's wrong, on a lot of levels.
Bastard Programmer from Hell :suss: "If you just follow the bacon Eddy, wherever it leads you, then you won't have to think about politics." -- Some Bell.