Well, I'd love to tell you, but it wouldn't do you any good because what you do depends on your network environment, its configuration, policies you have in place (if any), your app's requirements, if you have a certificate, if you're going to use this certificate for future apps, ... Basically, that's what all that documentation is for. There's a bunch of options to explore to do this. In a nutshell, you have to get the machines to trust your code, either the source folder, or registered assemblies, or certificate-based trust. How you do that depends on network environment and any policy management setup you have.
A guide to posting questions on CodeProject[^]
Dave Kreskowiak Microsoft MVP Visual Developer - Visual Basic
2006, 2007