If you read the first page you link to, you have: However, because Office applications also register their documents in the ROT, you can successfully attach to other instances by iterating the ROT looking for a specific document, attaching to this document, and then getting the Application object from this document. For a code example of iterating the ROT and looking for a document name, click the article number below to view the article in the Microsoft Knowledge Base:... You don't even have to reference each individual instance as all documents (from all instances of excel) is in the ROT. If you need the application object for a document, it's also there via the document object.