I'm afraid I either posted my original question very poorly, or you misunderstood. I know how to create a shortcut key, my problem is that when a control other than a text box control has the focus, the user does not have to press the Alt key to go to another control that has a shortcut (or accelerator) key. For example, assume the command buttons below where btn1 has the shortcut set to "b", and btn2 has the shortcut set to "u" btn1.Text = "&button1" btn2.Text = "b&utton2" If btn2 currently has the focus, the user only has to press the letter "b" for btn1 to get the focus. I would prefer if the user always had to press the "Alt" key before any shortcut is activated but as long as the focus is not on a textbox, the "Alt" keys is apparently now unnecessary. I know I can tackle this issue by ensuring the Alt key is pressed in the KeyDown event of non-textbox controls, but I'm hoping there is some global setting in Tools-Options that I do not know about that will quickly tackle this issue for any apps I may develop. Thank you...