I suppose I would opt for higher resolution for when I need it and change text size etc. with ctrl + scroll. I am spoiled though from using a true 4K 31" monitor and I can't imagine scaling down now. Strange thing I experienced is when I used the monitor in 3840 x 2160 mode icons and dialog boxes did not increase scale, but when I Switched to 4096 x 2160 mode, everything scaled appropriately and I find it very comfortable. With a monitor this size, I can use the single screen as two by using Window Key + left arrow and selecting the second app after that. Thank you Joan for another interesting question.
Rollin Shultz Bulletproof Designs LLC Windows Insider - Fast Track Motto: Ask for help when needed, help others when asked, and remember where you came from.