Yes, but it may get involved. You have to use Office Automation within c# Here is a link to get you started http://weblogs.asp.net/sbehera/archive/2003/12/12/43034.aspx

I assume you are going to do it via asp.net. If so, look here: http://aspnet.4guysfromrolla.com/articles/051802-1.aspx[^]. It will show you how to read a text file and use it as a string in your vb code.