Microsoft Dynamics formerly Microsoft Business Solutions covers a lot of territory. Their primary products are accounting solutions such as Great Plains, Axapta, and Navision, though that isn't the entire list. CRM is also a Dynamics product, as is Business Portal. They are all integrated to some extent with Office products such as Outlook, Excel, and Word, and they come with built in support for SharePoint Services. There are a great many ISV or 3rd party products being developed for them as well. Most of the work in the field is with these ISVs or in integration and customization for the end users. You don't have to know the product you are working with, but having some knowledge of it is a big advantage. There is a large support community for those who work with it, and Microsoft provides a lot of support as well.
Tom Garth Developer R. L. Nelson and Associates, Inc., Virginia